Le nostre pubblicazioni



Renal Oxygen Demand and Nephron Function: Is Glucose a Friend or Foe?
Gronda E, Palazzuoli A, Iacoviello M, Benevenuto M, Gabrielli D, Arduini A.
Int J Mol Sci. 2023 Jun 9; 24(12):9957.

Fibrosis of Peritoneal Membrane as Target of New Therapies in Peritoneal Dialysis.
Masola V, Bonomini M, Borrelli S, Di Liberato L, Vecchi L, Onisto M, Gambaro G, Palumbo R, Arduini A.
Int J Mol Sci. 2022 Apr 27;23(9):4831. PMID: 35563220

Mechanisms of action of SGLT2 inhibitors and their beneficial effects on the cardiorenal axis.
Gronda E, Lopaschuk GD, Arduini A, Santoro A, Benincasa G, Palazzuoli A, Gabrielli D, Napoli C.
Can J Physiol Pharmacol. 2022 Feb;100(2):93-106. PMID: 35112597

Aquaporin-1 Facilitates Transmesothelial Water Permeability: In Vitro and Ex Vivo Evidence and Possible Implications in Peritoneal Dialysis.
Piccapane F, Gerbino A, Carmosino M, Milano S, Arduini A, Debellis L, Svelto M, Caroppo R, Procino G.
Int J Mol Sci. 2021 Nov 21;22(22):12535. PMID: 34830416

[Which future solutions for peritoneal dialysis?].
Bonomini M, Di Liberato L, Rago C, Lombardi T, Sirolli V, Arduini A.
G Ital Nefrol. 2021 Oct 26;38(5):2021-vol5. PMID: 34713640

Insulin resistance in cardiovascular disease, uremia, and peritoneal dialysis.
Lambie M, Bonomini M, Davies SJ, Accili D, Arduini A, Zammit V.
Trends Endocrinol Metab. 2021 Sep;32(9):721-730. PMID: 34266706

How to Improve the Biocompatibility of Peritoneal Dialysis Solutions (without Jeopardizing the Patient's Health).
Bonomini M, Masola V, Procino G, Zammit V, Divino-Filho JC, Arduini A, Gambaro G.
Int J Mol Sci. 2021 Jul 26;22(15):7955. PMID: 34360717

Biological Effects of XyloCore, a Glucose Sparing PD Solution, on Mesothelial Cells: Focus on Mesothelial-Mesenchymal Transition, Inflammation and Angiogenesis.
Masola V, Bonomini M, Onisto M, Ferraro PM, Arduini A, Gambaro G.
Nutrients. 2021 Jun 30;13(7):2282. PMID: 34209455

Mild sodium reduction in peritoneal dialysis solution improves hypertension in end stage kidney disease: a case-report study.
Vecchi L, Bonomini M, Palumbo R, Arduini A, Borrelli S.
BMC Nephrol. 2021 May 8;22(1):170. PMID: 33964894

The osmo-metabolic approach: a novel and tantalizing glucose-sparing strategy in peritoneal dialysis.
Bonomini M, Zammit V, Divino-Filho JC, Davies SJ, Di Liberato L, Arduini A, Lambie M.
J Nephrol. 2021 Apr;34(2):503-519. PMID: 32767274

Endothelial Glycocalyx as a Regulator of Fibrotic Processes.
Masola V, Zaza G, Arduini A, Onisto M, Gambaro G.
Int J Mol Sci. 2021 Mar 15;22(6):2996. PMID: 33804258

A New Peritoneal Dialysis Solution Containing L-Carnitine and Xylitol for Patients on Continuous Ambulatory Peritoneal Dialysis: First Clinical Experience.
Rago C, Lombardi T, Di Fulvio G, Di Liberato L, Arduini A, Divino-Filho JC, Bonomini M.
Toxins (Basel). 2021 Feb 24;13(3):174. PMID: 33668249

A Novel Formulation of Glucose-Sparing Peritoneal Dialysis Solutions with l-Carnitine Improves Biocompatibility on Human Mesothelial Cells.
Piccapane F, Bonomini M, Castellano G, Gerbino A, Carmosino M, Svelto M, Arduini A, Procino G.
Int J Mol Sci. 2020 Dec 24;22(1):123. PMID: 33374405

Structure-based virtual screening to identify novel carnitine acetyltransferase activators.
Ombrato R, Console L, Righino B, Indiveri C, Arduini A, De Rosa MC.
J Mol Graph Model. 2020 Nov; 100:107692. PMID: 32759041

Proteomic Research in Peritoneal Dialysis.
Bonomini M, Borras FE, Troya-Saborido M, Carreras-Planella L, Di Liberato L, Arduini A.
Int J Mol Sci. 2020 Jul 31;21(15):5489. PMID: 32752018

Identification of trimethylamine N-oxide (TMAO)-producer phenotype is interesting, but is it helpful?
Arduini A, Zammit VA, Bonomini M.
Gut. 2020 Feb;69(2):400-401. PMID: 30635410

Current Opinion on Usage of L-Carnitine in End-Stage Renal Disease Patients on Peritoneal Dialysis.
Bonomini M, Di Liberato L, Zammit V, Arduini A.
Molecules. 2019 Sep 23;24(19):3449. PMID: 31547545 "

Acetate transport into mitochondria does not require a carnitine shuttle mechanism.
Arduini A, Zammit V.
Magn Reson Med. 2017 Jan;77(1):11. PMID: 27851883

Effect of peritoneal dialysis fluid containing osmo-metabolic agents on human endothelial cells.
Bonomini M, Di Silvestre S, Di Tomo P, Di Pietro N, Mandatori D, Di Liberato L, Sirolli V, Chiarelli F, Indiveri C, Pandolfi A, Arduini A.
Drug Des Devel Ther. 2016 Nov 28;10:3925-3932. PMID: 27932866

A tennis lesson: sharp practice in the science behind the Sharapova case.
Arduini A, Zammit VA.
Postgrad Med J. 2016 Aug;92(1090):429-30. PMID: 27252310

A Moderate Carnitine Deficiency Exacerbates Isoproterenol-Induced Myocardial Injury in Rats.
Giudice PL, Bonomini M, Arduini A.
Cardiovasc Drugs Ther. 2016 Apr;30(2):119-27. PMID: 26838729

Acetylcholine and acetylcarnitine transport in peritoneum: Role of the SLC22A4 (OCTN1) transporter.
Pochini L, Scalise M, Di Silvestre S, Belviso S, Pandolfi A, Arduini A, Bonomini M, Indiveri C.
Biochim Biophys Acta. 2016 Apr;1858(4):653-60. PMID: 26724204

L-Carnitine status in end-stage renal disease patients on automated peritoneal dialysis.
Di Liberato L, Arduini A, Rossi C, Di Castelnuovo A, Posari C, Sacchetta P, Urbani A, Bonomini M.
J Nephrol. 2014 Dec;27(6):699-706. PMID: 24599831

Gut microbiota metabolism of L-carnitine and cardiovascular risk.
Ussher JR, Lopaschuk GD, Arduini A.
Atherosclerosis. 2013 Dec;231(2):456-61. PMID: 24267266

Effect of an L-carnitine-containing peritoneal dialysate on insulin sensitivity in patients treated with CAPD: a 4-month, prospective, multicenter randomized trial.
Bonomini M, Di Liberato L, Del Rosso G, Stingone A, Marinangeli G, Consoli A, Bertoli S, De Vecchi A, Bosi E, Russo R, Corciulo R, Gesualdo L, Giorgino F, Cerasoli P, Di Castelnuovo A, Monaco MP, Shockley T, Rossi C, Arduini A.
Am J Kidney Dis. 2013 Nov;62(5):929-38. PMID: 23725973

In vitro microbiology studies on a new peritoneal dialysis connector.
Di Bonaventura G, Cerasoli P, Pompilio A, Arrizza F, Di Liberato L, Stingone A, Sirolli V, Arduini A, Bonomini M.
Perit Dial Int. 2012 Sep-Oct;32(5):552-7. PMID: 22302771

Toward personalized hemodialysis by low molecular weight amino-containing compounds: future perspective of patient metabolic fingerprint.
Sirolli V, Rossi C, Di Castelnuovo A, Felaco P, Amoroso L, Zucchelli M, Ciavardelli D, Di Ilio C, Sacchetta P, Bernardini S, Arduini A, Bonomini M, Urbani A.
Blood Transfus. 2012 May;10 Suppl 2(Suppl 2):s78-88. PMID: 22890273

L-carnitine is an osmotic agent suitable for peritoneal dialysis.
Bonomini M, Pandolfi A, Di Liberato L, Di Silvestre S, Cnops Y, Di Tomo P, D'Arezzo M, Monaco MP, Giardinelli A, Di Pietro N, Devuyst O, Arduini A.
Kidney Int. 2011 Sep;80(6):645-54. PMID: 21525850 "

Pharmacological use of L-carnitine in uremic anemia: has its full potential been exploited?
Bonomini M, Zammit V, Pusey CD, De Vecchi A, Arduini A.
Pharmacol Res. 2011 Mar;63(3):157-64. PMID: 21138768 "

Carnitine, mitochondrial function and therapy.
Zammit VA, Ramsay RR, Bonomini M, Arduini A.
Adv Drug Deliv Rev. 2009 Nov 30;61(14):1353-62. PMID: 19716391

Propionyl-L-carnitine prevents early graft dysfunction in allogeneic rat kidney transplantation.
Azzollini N, Cugini D, Cassis P, Pezzotta A, Gagliardini E, Abbate M, Arduini A, Peschechera A, Remuzzi G, Noris M.
Kidney Int. 2008 Dec;74(11):1420-8. PMID: 19008910

Carnitine in metabolic disease: potential for pharmacological intervention.
Arduini A, Bonomini M, Savica V, Amato A, Zammit V.
Pharmacol Ther. 2008 Nov;120(2):149-56. PMID: 18793670.

Effect of L-carnitine administration on erythrocyte survival in haemodialysis patients.
Arduini A, Bonomini M, Clutterbuck EJ, Laffan MA, Pusey CD.
Nephrol Dial Transplant. 2006 Sep;21(9):2671-2. PMID: 16611680

Prevention of peritoneal sclerosis: a new proposal to substitute glucose with carnitine dialysis solution (biocompatibility testing in vitro and in rabbits).
Gaggiotti E, Arduini A, Bonomini M, Valentini G, Sacchi G, Sansoni E, Salvo D, Di Paolo N.
Int J Artif Organs. 2005 Feb;28(2):177-87. PMID: 15770606

Red blood cells may contribute to hypercoagulability in uraemia via enhanced surface exposure of phosphatidylserine.
Bonomini M, Sirolli V, Merciaro G, Antidormi T, Di Liberato L, Brummer U, Papponetti M, Cappelli P, Di Gregorio P, Arduini A.
Nephrol Dial Transplant. 2005 Feb;20(2):361-6. PMID: 15598665

Increased platelet phosphatidylserine exposure and caspase activation in chronic uremia.
Bonomini M, Dottori S, Amoroso L, Arduini A, Sirolli V.
J Thromb Haemost. 2004 Aug;2(8):1275-81. PMID: 15304031 "

L-carnitine and its possible role in red cell and platelet storage.
Sweeney JD, Arduini A.
Transfus Med Rev. 2004 Jan;18(1):58-65. PMID: 14689378

Removal of uraemic plasma factor(s) using different dialysis modalities reduces phosphatidylserine exposure in red blood cells.
Bonomini M, Ballone E, Di Stante S, Bucciarelli T, Dottori S, Arduini A, Urbani A, Sirolli V.
Nephrol Dial Transplant. 2004 Jan;19(1):68-74. PMID: 14671041

Involvement of phosphatidylserine exposure in the recognition and phagocytosis of uremic erythrocytes.
Bonomini M, Sirolli V, Reale M, Arduini A.
Am J Kidney Dis. 2001 Apr;37(4):807-14. PMID: 11273881

Increased erythrocyte phosphatidylserine exposure in chronic renal failure.
Bonomini M, Sirolli V, Settefrati N, Dottori S, Di Liberato L, Arduini A.
J Am Soc Nephrol. 1999 Sep;10(9):1982-90. PMID: 10477151